7SU9
KRAS-G12D specific TCR9a in complex with C*05-GADGVGKSL
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | D | TCR9a alpha chain | polymer | 206 | 22651.1 | 1 | Homo sapiens (human) | ||
2 | E | TCR9a beta chain | polymer | 244 | 27493.4 | 1 | Homo sapiens (human) | ||
3 | A | MHC class I antigen | polymer | 280 | 32432.8 | 1 | UniProt (A0A7T3RIQ2) Pfam (PF00129) Pfam (PF07654) UniProt (by SIFTS) (A2BF26) In PDB | Homo sapiens (Human) | |
4 | B | Beta-2-microglobulin | polymer | 100 | 11879.4 | 1 | UniProt (P61769) Pfam (PF07654) In PDB | Homo sapiens (Human) | |
5 | C | KRAS-G12D-9mer with A18L substitution | polymer | 9 | 803.9 | 1 | Homo sapiens | ||
6 | D, E | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
7 | E, A | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
8 | E | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
9 | water | water | 18.0 | 454 | Chemie (HOH) |
Sequence modifications
B: 1 - 99 (UniProt: P61769)
PDB | External Database | Details |
---|---|---|
Met 0 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 5 |
Total formula weight | 95260.5 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 424.9 | |
All* | Total formula weight | 95685.4 |