7SU8

DIHYDRONEOPTERIN ALDOLASE (DHNA) FROM YERSINIA PESTIS with alkylated Cys50 CO-CRYSTALLIZED with 7,8-dihydroneopterin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	7,8-dihydroneopterin aldolase	polymer	143	16149.2	2	UniProt (Q8CZR7) Pfam (PF02152) UniProt (by SIFTS) (A0A5P8YJX5) In PDB	Yersinia pestis
2	A, B	1-ETHYL-PYRROLIDINE-2,5-DIONE	non-polymer		127.1	2	Chemie (NEN)
3	A, B	2-AMINO-6-HYDROXYMETHYL-7,8-DIHYDRO-3H-PTERIDIN-4-ONE	non-polymer		195.2	2	Chemie (PH2)
4	B	(4S)-2-METHYL-2,4-PENTANEDIOL	non-polymer		118.2	2	Chemie (MPD)
5	B	2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL	non-polymer		122.1	1	Chemie (TRS)
6		water	water		18.0	60	Chemie (HOH)

Sequence modifications

A, B: 1 - 119 (UniProt: Q8CZR7)

PDB	External Database	Details
Met -23	-	expression tag
His -22	-	expression tag
His -21	-	expression tag
His -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
Ser -16	-	expression tag
Ser -15	-	expression tag
Gly -14	-	expression tag
Val -13	-	expression tag
Asp -12	-	expression tag
Leu -11	-	expression tag
Gly -10	-	expression tag
Thr -9	-	expression tag
Glu -8	-	expression tag
Asn -7	-	expression tag
Leu -6	-	expression tag
Tyr -5	-	expression tag
Phe -4	-	expression tag
Gln -3	-	expression tag
Ser -2	-	expression tag
Asn -1	-	expression tag
Ala 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	32298.3
Non-Polymers*	Number of molecules	7
	Total formula weight	1003.1
All*	Total formula weight	33301.5

*Water molecules are not included.