7SU4

Dihydroneopterin aldolase (DHNA) Tyr53Phe from Yersinia pestis co-crystallized with 7,8-dihydroneopterin

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	7,8-dihydroneopterin aldolase	polymer	143	16133.2	4	UniProt (Q8CZR7) Pfam (PF02152)	Yersinia pestis
2	E, I, L, M (A, B, C, D)	2-AMINO-7,8-DIHYDRO-6-(1,2,3-TRIHYDROXYPROPYL)-4(1H)-PTERIDINONE	non-polymer		255.2	4	Chemie (NPR)
3	F, G (A)	2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL	non-polymer		122.1	2	Chemie (TRS)
4	H, J, K, N (A, B, D)	GLYCEROL	non-polymer		92.1	4	Chemie (GOL)
5	O, P, Q, R (A, B, C, D)	water	water		18.0	625	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 119 (UniProt: Q8CZR7)

PDB	External Database	Details
Met -23	-	initiating methionine
His -22	-	expression tag
His -21	-	expression tag
His -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
Ser -16	-	expression tag
Ser -15	-	expression tag
Gly -14	-	expression tag
Val -13	-	expression tag
Asp -12	-	expression tag
Leu -11	-	expression tag
Gly -10	-	expression tag
Thr -9	-	expression tag
Glu -8	-	expression tag
Asn -7	-	expression tag
Leu -6	-	expression tag
Tyr -5	-	expression tag
Phe -4	-	expression tag
Gln -3	-	expression tag
Ser -2	-	expression tag
Asn -1	-	expression tag
Ala 0	-	expression tag
Phe 53	Tyr 54	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	64532.7
Non-Polymers*	Number of molecules	10
	Total formula weight	1633.6
All*	Total formula weight	66166.3

*Water molecules are not included.