7STX

Cryo-EM structure of human NatB in complex with CoA-Alpha-Synuclein

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	N-alpha-acetyltransferase 20	polymer	178	20390.1	1	UniProt (P61599) Pfam (PF00583)	Homo sapiens (human)	Methionine N-acetyltransferase,N-acetyltransferase 5,N-terminal acetyltransferase B complex catalytic subunit NAA20,N-terminal acetyltransferase B complex catalytic subunit NAT5,NatB complex subunit NAT5,NatB catalytic subunit
2	B (B)	N-alpha-acetyltransferase 25, NatB auxiliary subunit	polymer	956	109642.3	1	UniProt (Q14CX7) Pfam (PF09797)	Homo sapiens (Human)	Mitochondrial distribution and morphology protein 20,N-terminal acetyltransferase B complex subunit MDM20,NatB complex subunit MDM20,N-terminal acetyltransferase B complex subunit NAA25,p120
3	C (C)	Alpha-synuclein	polymer	6	667.8	1	UniProt (P37840)	Homo sapiens (human)	Non-A beta component of AD amyloid,Non-A4 component of amyloid precursor,NACP
4	D (A)	COENZYME A	non-polymer		767.5	1	Chemie (COA)

Sequence modifications

B: 13 - 40 (PDB: 7STX)
B: 45 - 972 (UniProt: Q14CX7)
C: 1 - 5 (UniProt: P37840)

PDB	External Database	Details
Ace 0	-	acetylation

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	130700.2
Non-Polymers*	Number of molecules	1
	Total formula weight	767.5
All*	Total formula weight	131467.8

*Water molecules are not included.