7SSK
Human P300 complexed with a glycine-based inhibitor
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Histone acetyltransferase p300 | polymer | 569 | 66193.4 | 1 | UniProt (Q09472) Pfam (PF00439) Pfam (PF06001) Pfam (PF08214) In PDB | Homo sapiens (Human) | p300 HAT,E1A-associated protein p300,Histone butyryltransferase p300,Histone crotonyltransferase p300,Protein 2-hydroxyisobutyryltransferase p300,Protein lactyltransferas p300,Protein propionyltransferase p300 |
2 | A | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
3 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
4 | A | N-[2-(4-methoxyanilino)-2-oxoethyl]-N-methyl-1-phenylcyclopentane-1-carboxamide | non-polymer | 366.5 | 1 | Chemie (C3I) | |||
5 | A | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
6 | water | water | 18.0 | 222 | Chemie (HOH) |
Sequence modifications
A: 1048 - 1576 (UniProt: Q09472)
A: 1582 - 1664 (UniProt: Q09472)
PDB | External Database | Details |
---|---|---|
Gly 1039 | - | expression tag |
Gly 1040 | - | expression tag |
His 1041 | - | expression tag |
His 1042 | - | expression tag |
His 1043 | - | expression tag |
His 1044 | - | expression tag |
His 1045 | - | expression tag |
His 1046 | - | expression tag |
Gly 1047 | - | expression tag |
Phe 1467 | Tyr 1467 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Ser 1577 | - | linker |
Gly 1578 | - | linker |
Gly 1579 | - | linker |
Ser 1580 | - | linker |
Gly 1581 | - | linker |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 66193.4 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 618.4 | |
All* | Total formula weight | 66811.8 |