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7SPR

Crystal structure of SMG1 mutant (G28C/P206C/Q34P/A37P/M176V/G177A/M294R/F278N)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
LIP1, secretory lipase (Family 3)polymer27730896.71UniProt (A8PUY1)
Pfam (PF01764)
Malassezia globosa (strain ATCC MYA-4612 / CBS 7966) (Dandruff-associated fungus)
2B
(B)
2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched424.41In PDB
GlyTouCan (G42666HT)
3C
(A)
waterwater18.0225Chemie (HOH)
Sequence modifications
A: 28 - 304 (UniProt: A8PUY1)
PDBExternal DatabaseDetails
Cys 28Gly 28engineered mutation
Pro 34Gln 34engineered mutation
Pro 37Ala 37engineered mutation
Val 176Met 176engineered mutation
Ala 177Gly 177engineered mutation
Cys 206Pro 206engineered mutation
Asn 278Phe 278engineered mutation
Arg 294Met 294engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight30896.7
BranchedNumber of molecules1
Total formula weight424.4
All*Total formula weight31321.1
*Water molecules are not included.

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PDB entries from 2025-06-18

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