7SP0
Crystal structure of human SFPQ L534I mutant in complex with zinc
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Splicing factor, proline- and glutamine-rich | polymer | 263 | 30094.0 | 2 | UniProt (P23246) Pfam (PF00076) Pfam (PF08075) In PDB | Homo sapiens (Human) | 100 kDa DNA-pairing protein,hPOMp100,DNA-binding p52/p100 complex,100 kDa subunit,Polypyrimidine tract-binding protein-associated-splicing factor,PSF,PTB-associated-splicing factor |
| 2 | A, B | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | water | water | 18.0 | 277 | Chemie (HOH) |
Sequence modifications
A, B: 276 - 535 (UniProt: P23246)
| PDB | External Database | Details |
|---|---|---|
| Gly 273 | - | expression tag |
| Ala 274 | - | expression tag |
| Met 275 | - | expression tag |
| Ile 534 | Leu 534 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 60188.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 130.8 | |
| All* | Total formula weight | 60318.9 |
