7SJO

HtrA1S328A:Fab15H6.v4 complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C	Serine protease HTRA1	polymer	235	25714.4	3	UniProt (Q92743) Pfam (PF13365) In PDB	Homo sapiens (human)	High-temperature requirement A serine peptidase 1,L56,Serine protease 11
2	E, H, I	Fab15H6.v4 Heavy Chain	polymer	250	26769.0	3		Homo sapiens
3	F, J, L	Fab15H6.v4 Light Chain	polymer	236	25717.7	3		Homo sapiens

Sequence modifications

A, B, C: 161 - 379 (UniProt: Q92743)

PDB	External Database	Details
Met 145	-	expression tag
His 146	-	expression tag
His 147	-	expression tag
His 148	-	expression tag
His 149	-	expression tag
His 150	-	expression tag
His 151	-	expression tag
Gly 152	-	expression tag
Glu 153	-	expression tag
Asn 154	-	expression tag
Leu 155	-	expression tag
Tyr 156	-	expression tag
Phe 157	-	expression tag
Gln 158	-	expression tag
Gly 159	-	expression tag
Ser 160	-	expression tag
Ala 328	Ser 328	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	9
	Total formula weight	234603.3
All*	Total formula weight	234603.3

*Water molecules are not included.