7SHU
IgE-Fc in complex with omalizumab variant C02
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | E, C | omalizumab variant C02 VH | polymer | 123 | 13437.8 | 2 | Homo sapiens | ||
| 2 | F, D | omalizumab variant C02 VL | polymer | 134 | 14618.8 | 2 | Homo sapiens | ||
| 3 | B, A | Immunoglobulin heavy constant epsilon | polymer | 220 | 24566.7 | 2 | UniProt (P01854) Pfam (PF07654) In PDB | Homo sapiens (Human) | Ig epsilon chain C region,Ig epsilon chain C region ND |
| 4 | G | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G81315DD) | |||
| 5 | H | beta-D-mannopyranose-(1-4)-[alpha-D-mannopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 545.5 | 1 | In PDB GlyTouCan (G14523PK) | |||
| 6 | E | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 7 | E | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 8 | E | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 9 | water | water | 18.0 | 13 | Chemie (HOH) |
Sequence modifications
B, A: 328 - 545 (UniProt: P01854)
| PDB | External Database | Details |
|---|---|---|
| Gly 326 | - | expression tag |
| Ser 327 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 105246.6 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 1294.2 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 378.2 | |
| All* | Total formula weight | 106919.0 |
