7SHQ

Structure of a functional construct of eukaryotic elongation factor 2 kinase in complex with calmodulin.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Eukaryotic elongation factor 2 kinase,Eukaryotic elongation factor 2 kinase	polymer	531	60380.7	1	UniProt (O00418) Pfam (PF02816) In PDB	Homo sapiens (Human)	eEF-2 kinase,eEF-2K,Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase,eEF-2 kinase,eEF-2K,Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase
2	B	Calmodulin-1	polymer	148	16721.3	1	UniProt (P0DP23) Pfam (PF13499) In PDB	Homo sapiens (Human)
3	A	ZINC ION	non-polymer		65.4	1	Chemie (ZN)
4	A, B	MAGNESIUM ION	non-polymer		24.3	5	Chemie (MG)
5	B	CALCIUM ION	non-polymer		40.1	2	Chemie (CA)
6		water	water		18.0	143	Chemie (HOH)

Sequence modifications

A: 70 - 358 (UniProt: O00418)
A: 490 - 725 (UniProt: O00418)

PDB	External Database	Details
Gly 484	-	linker
Gly 485	-	linker
Gly 486	-	linker
Gly 487	-	linker
Gly 488	-	linker
Gly 489	-	linker

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	77102.1
Non-Polymers*	Number of molecules	8
	Total formula weight	267.1
All*	Total formula weight	77369.2

*Water molecules are not included.