7SH4

CD1a-phosphatidylglycerol binary structure

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	T-cell surface glycoprotein CD1a	polymer	285	32464.4	1	UniProt (P06126) Pfam (PF16497) Pfam (PF07654)	Homo sapiens (Human)	T-cell surface antigen T6/Leu-6,hTa1 thymocyte antigen
2	B (B)	Beta-2-microglobulin	polymer	108	12560.1	1	UniProt (P61769) Pfam (PF07654)	Homo sapiens (Human)
3	C (A)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)
4	D (A)	(21R,24R,27S)-24,27,28-trihydroxy-18,24-dioxo-19,23,25-trioxa-24lambda~5~-phosphaoctacosan-21-yl (9Z)-octadec-9-enoate	non-polymer		777.1	1	Chemie (MW9)
5	E, G (A)	1,2-ETHANEDIOL	non-polymer		62.1	2	Chemie (EDO)
6	F (A)	2-(N-MORPHOLINO)-ETHANESULFONIC ACID	non-polymer		195.2	1	Chemie (MES)
7	H, I (B)	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	2	Chemie (PEG)
8	J, K (A, B)	water	water		18.0	307	Chemie (HOH)

Sequence modifications

A: 1 - 278 (UniProt: P06126)

PDB	External Database	Details
Thr 2	Asp 19	conflict
Ile 13	Thr 30	conflict
Trp 51	Cys 68	conflict
Gly 279	-	expression tag
Ser 280	-	expression tag
Leu 281	-	expression tag
Val 282	-	expression tag
Pro 283	-	expression tag
Arg 284	-	expression tag
Gly 285	-	expression tag

B: 2 - 100 (UniProt: P61769)

PDB	External Database	Details
Gly 1	-	expression tag
Gly 101	-	expression tag
Ser 102	-	expression tag
Leu 103	-	expression tag
Val 104	-	expression tag
Pro 105	-	expression tag
Arg 106	-	expression tag
Gly 107	-	expression tag
Ser 108	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	45024.5
Non-Polymers*	Number of molecules	7
	Total formula weight	1529.9
All*	Total formula weight	46554.4

*Water molecules are not included.