7SGU
Papain-Like Protease of SARS CoV-2, C111S mutant, in complex with PLP_Snyder608 inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Papain-like protease | polymer | 318 | 35927.7 | 1 | UniProt (P0DTC1) Pfam (PF08715) UniProt (by SIFTS) (P0DTD1) In PDB | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) | Non-structural protein 3, nsp3, PL2-PRO, Papain-like proteinase, PL-PRO |
| 2 | A | 5-amino-N-(naphthalen-1-yl)pyridine-3-carboxamide | non-polymer | 263.3 | 1 | Chemie (9EI) | |||
| 3 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | A | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 5 | A | FORMIC ACID | non-polymer | 46.0 | 2 | Chemie (FMT) | |||
| 6 | water | water | 18.0 | 222 | Chemie (HOH) |
Sequence modifications
A: 1 - 315 (UniProt: P0DTC1)
| PDB | External Database | Details |
|---|---|---|
| Ser -2 | - | expression tag |
| Asn -1 | - | expression tag |
| Ala 0 | - | expression tag |
| Ser 111 | Cys 1674 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 35927.7 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 491.7 | |
| All* | Total formula weight | 36419.4 |
