7SG2

XPA5 TCR in complex with HLA-DQ2-omega1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, F)	HLA class II histocompatibility antigen, DQ alpha 1 chain	polymer	183	20683.1	2	UniProt (P01909) Pfam (PF00993) Pfam (PF07654)	Homo sapiens (Human)	DC-1 alpha chain,DC-alpha,HLA-DCA,MHC class II DQA1
2	B, D (B, G)	MHC class II HLA-DQ-beta-1	polymer	205	23556.5	2	UniProt (O19712) Pfam (PF00969) Pfam (PF07654) UniProt (by SIFTS) (Q5Y7D3)	Homo sapiens (Human)
3	E, I (D, I)	T-cell receptor, xpa5, alpha chain	polymer	203	22661.2	2		Homo sapiens (Human)
4	F, J (E, J)	T-cell receptor, xpa5, beta chain	polymer	246	27515.7	2		Homo sapiens (Human)
5	G, H (C, H)	DQ2-glia-omega1 peptide	polymer	13	1455.6	2		Homo sapiens (Human)
6	K, O (A, F)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)
7	L, R, S (A, J)	1,2-ETHANEDIOL	non-polymer		62.1	3	Chemie (EDO)
8	M, P (A, F)	ACETATE ION	non-polymer		59.0	2	Chemie (ACT)
9	N, Q (B, E)	CALCIUM ION	non-polymer		40.1	2	Chemie (CA)
10	T, U, V, W (A, B, F, E)	water	water		18.0	7	Chemie (HOH)

Sequence modifications

B, G: 1 - 192 (UniProt: O19712)

PDB	External Database	Details
Gly -12	-	expression tag
Gly -11	-	expression tag
Ser -10	-	expression tag
Ile -9	-	expression tag
Glu -8	-	expression tag
Gly -7	-	expression tag
Arg -6	-	expression tag
Gly -5	-	expression tag
Gly -4	-	expression tag
Ser -3	-	expression tag
Gly -2	-	expression tag
Ala -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	10
	Total formula weight	191744.1
Non-Polymers*	Number of molecules	9
	Total formula weight	826.9
All*	Total formula weight	192571.0

*Water molecules are not included.