7SFG
Human DNMT1(729-1600) Bound to Zebularine-Containing 12mer dsDNA and Cofactor SAM
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DNA (cytosine-5)-methyltransferase 1 | polymer | 874 | 98803.6 | 1 | UniProt (P26358) Pfam (PF01426) Pfam (PF00145) | Homo sapiens (Human) | Dnmt1,CXXC-type zinc finger protein 9,DNA methyltransferase HsaI,M.HsaI,MCMT |
| 2 | B (C) | DNA Strand 1 | polymer | 12 | 3678.4 | 1 | Homo sapiens | ||
| 3 | C (D) | DNA Strand 2 | polymer | 12 | 3665.4 | 1 | Homo sapiens | ||
| 4 | D, E (A) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 5 | F (A) | S-ADENOSYLMETHIONINE | non-polymer | 398.4 | 1 | Chemie (SAM) | |||
| 6 | G (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 7 | H, I, J, K, L... (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 6 | Chemie (EDO) | |||
| 8 | N, O, P (A, C, D) | water | water | 18.0 | 287 | Chemie (HOH) |
Sequence modifications
A: 729 - 1600 (UniProt: P26358)
| PDB | External Database | Details |
|---|---|---|
| His 727 | - | expression tag |
| Met 728 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 106147.3 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 993.8 | |
| All* | Total formula weight | 107141.1 |
