7SFG
Human DNMT1(729-1600) Bound to Zebularine-Containing 12mer dsDNA and Cofactor SAM
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | DNA (cytosine-5)-methyltransferase 1 | polymer | 874 | 98803.6 | 1 | UniProt (P26358) Pfam (PF01426) Pfam (PF00145) In PDB | Homo sapiens (Human) | Dnmt1,CXXC-type zinc finger protein 9,DNA methyltransferase HsaI,M.HsaI,MCMT |
2 | C | DNA Strand 1 | polymer | 12 | 3678.4 | 1 | Homo sapiens | ||
3 | D | DNA Strand 2 | polymer | 12 | 3665.4 | 1 | Homo sapiens | ||
4 | A | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
5 | A | S-ADENOSYLMETHIONINE | non-polymer | 398.4 | 1 | Chemie (SAM) | |||
6 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
7 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 6 | Chemie (EDO) | |||
8 | water | water | 18.0 | 287 | Chemie (HOH) |
Sequence modifications
A: 729 - 1600 (UniProt: P26358)
PDB | External Database | Details |
---|---|---|
His 727 | - | expression tag |
Met 728 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 106147.3 | |
Non-Polymers* | Number of molecules | 10 |
Total formula weight | 993.8 | |
All* | Total formula weight | 107141.1 |