7SED
Crystal structure of human Fibrillarin in complex with compound 2a
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | rRNA 2'-O-methyltransferase fibrillarin | polymer | 242 | 26681.6 | 1 | UniProt (P22087) Pfam (PF01269) | Homo sapiens (Human) | 34 kDa nucleolar scleroderma antigen,Histone-glutamine methyltransferase,U6 snRNA 2'-O-methyltransferase fibrillarin |
| 2 | B (A) | N-(piperidin-4-yl)-6-(trifluoromethyl)pyrimidin-4-amine | non-polymer | 246.2 | 1 | Chemie (8VD) | |||
| 3 | C (A) | FORMIC ACID | non-polymer | 46.0 | 1 | Chemie (FMT) | |||
| 4 | D (A) | water | water | 18.0 | 89 | Chemie (HOH) |
Sequence modifications
A: 83 - 321 (UniProt: P22087)
| PDB | External Database | Details |
|---|---|---|
| Ser 80 | - | expression tag |
| Asn 81 | - | expression tag |
| Ala 82 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 26681.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 292.3 | |
| All* | Total formula weight | 26973.8 |
