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7SE7

Crystal structure of human Fibrillarin in complex with S-adenosyl-L-methionine

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
rRNA 2'-O-methyltransferase fibrillarinpolymer24226681.61UniProt (P22087)
Pfam (PF01269)
Homo sapiens (Human)34 kDa nucleolar scleroderma antigen,Histone-glutamine methyltransferase,U6 snRNA 2'-O-methyltransferase fibrillarin
2B
(A)
S-ADENOSYLMETHIONINEnon-polymer398.41Chemie (SAM)
3C
(A)
waterwater18.0189Chemie (HOH)
Sequence modifications
A: 83 - 321 (UniProt: P22087)
PDBExternal DatabaseDetails
Ser 80-expression tag
Asn 81-expression tag
Ala 82-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight26681.6
Non-Polymers*Number of molecules1
Total formula weight398.4
All*Total formula weight27080.0
*Water molecules are not included.

242500

PDB entries from 2025-10-01

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