7SBU

Crystal structure of SARS-CoV-2 spike protein receptor-binding domain in complex with a highly potent antibody J08 Fab

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Spike protein S1	polymer	205	23104.9	1	UniProt (P0DTC2) Pfam (PF09408) In PDB	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2)
2	H	J08 Fab heavy chain	polymer	228	24427.4	1		Homo sapiens
3	L	J08 Fab light chain	polymer	210	22754.2	1		Homo sapiens
4	A	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)
5	H, L	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
6		water	water		18.0	140	Chemie (HOH)

Sequence modifications

A: 333 - 530 (UniProt: P0DTC2)

PDB	External Database	Details
Gly 531	-	expression tag
His 532	-	expression tag
His 533	-	expression tag
His 534	-	expression tag
His 535	-	expression tag
His 536	-	expression tag
His 537	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	70286.6
Non-Polymers*	Number of molecules	3
	Total formula weight	405.4
All*	Total formula weight	70692.0

*Water molecules are not included.