7SBN
Human glutaminase C (Y466W) with L-Gln, closed conformation
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Isoform 3 of Glutaminase kidney isoform, mitochondrial | polymer | 539 | 59480.6 | 4 | UniProt (O94925) Pfam (PF17959) Pfam (PF04960) In PDB | Homo sapiens (Human) | GLS,K-glutaminase,L-glutamine amidohydrolase |
2 | A, B, C, D | GLUTAMINE | non-polymer | 146.1 | 4 | Chemie (GLN) | |||
3 | water | water | 18.0 | 341 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 72 - 598 (UniProt: O94925)
PDB | External Database | Details |
---|---|---|
Met 60 | - | initiating methionine |
Arg 61 | - | expression tag |
Gly 62 | - | expression tag |
Ser 63 | - | expression tag |
His 64 | - | expression tag |
His 65 | - | expression tag |
His 66 | - | expression tag |
His 67 | - | expression tag |
His 68 | - | expression tag |
His 69 | - | expression tag |
Gly 70 | - | expression tag |
Ser 71 | - | expression tag |
Trp 466 | Tyr 466 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 237922.5 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 584.6 | |
All* | Total formula weight | 238507.1 |