7SBK
Closed state of pre-fusion SARS-CoV-2 Delta variant spike protein
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (B, A, C) | Spike glycoprotein | polymer | 1308 | 144726.9 | 3 | UniProt (P0DTC2) Pfam (PF16451) Pfam (PF09408) Pfam (PF19209) Pfam (PF01601) | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2) | S glycoprotein,E2,Peplomer protein |
| 2 | AA, BA, D, DA, E... (a, b, D, d, E...) | alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 27 | In PDB GlyTouCan (G62182OO) | |||
| 3 | CA, G, R (c, G, R) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 3 | In PDB GlyTouCan (G42666HT) | |||
| 4 | FA, J, U (f, J, U) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 3 | In PDB GlyTouCan (G21290RB) | |||
| 5 | AB, BB, CB, DB, EB... (C, B, A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 21 | Chemie (NAG) |
Sequence modifications
B, A, C: 1 - 1273 (UniProt: P0DTC2)
| PDB | External Database | Details |
|---|---|---|
| Arg 19 | Thr 19 | variant |
| Asp 142 | Gly 142 | variant |
| - | Glu 156 | deletion |
| - | Phe 157 | deletion |
| Gly 156 | Arg 158 | variant |
| Arg 452 | Leu 452 | variant |
| Lys 478 | Thr 478 | variant |
| Gly 614 | Asp 614 | variant |
| Arg 681 | Pro 681 | variant |
| Asn 950 | Asp 950 | variant |
| Leu 1274 | - | expression tag |
| Glu 1275 | - | expression tag |
| Ser 1276 | - | expression tag |
| Gly 1277 | - | expression tag |
| Gly 1278 | - | expression tag |
| Gly 1279 | - | expression tag |
| Ser 1280 | - | expression tag |
| Ala 1281 | - | expression tag |
| Trp 1282 | - | expression tag |
| Ser 1283 | - | expression tag |
| His 1284 | - | expression tag |
| Pro 1285 | - | expression tag |
| Gln 1286 | - | expression tag |
| Phe 1287 | - | expression tag |
| Glu 1288 | - | expression tag |
| Lys 1289 | - | expression tag |
| Gly 1290 | - | expression tag |
| Gly 1291 | - | expression tag |
| Gly 1292 | - | expression tag |
| Ser 1293 | - | expression tag |
| Gly 1294 | - | expression tag |
| Gly 1295 | - | expression tag |
| Gly 1296 | - | expression tag |
| Ser 1297 | - | expression tag |
| Gly 1298 | - | expression tag |
| Gly 1299 | - | expression tag |
| Ser 1300 | - | expression tag |
| Ser 1301 | - | expression tag |
| Ala 1302 | - | expression tag |
| Trp 1303 | - | expression tag |
| Ser 1304 | - | expression tag |
| His 1305 | - | expression tag |
| Pro 1306 | - | expression tag |
| Gln 1307 | - | expression tag |
| Phe 1308 | - | expression tag |
| Glu 1309 | - | expression tag |
| Lys 1310 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 434180.8 | |
| Branched | Number of molecules | 33 |
| Total formula weight | 18821.5 | |
| Non-Polymers* | Number of molecules | 21 |
| Total formula weight | 4645.4 | |
| All* | Total formula weight | 457647.6 |
