7S82
Cryo-EM structure of SARS-CoV-2 Main protease C145S in complex with N-terminal peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, B, D | 3C-like proteinase | polymer | 314 | 34567.4 | 4 | UniProt (P0DTD1) Pfam (PF05409) In PDB | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) | 3CL-PRO, 3CLp, Main protease, Mpro, Non-structural protein 5, nsp5, SARS coronavirus main proteinase |
Sequence modifications
A, C, B, D: -4 - 306 (UniProt: P0DTD1)
| PDB | External Database | Details |
|---|---|---|
| Gly -7 | - | expression tag |
| Ala -6 | - | expression tag |
| Met -5 | - | expression tag |
| Ser 145 | Cys 3408 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 138269.5 | |
| All* | Total formula weight | 138269.5 |
