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7S7X

Crystal structure of iCytSnFR Cytisine Sensor precursor binding protein with varenicline bound

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C
(A, B, C)
iNicSnFR 4.0 Fluorescent Nicotine Sensor precursor binding proteinpolymer29333103.93Thermoanaerobacter sp. X513
2D, F, I
(A, B, C)
VARENICLINEnon-polymer211.33Chemie (QMR)
3E, G, J
(A, B, C)
2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACIDnon-polymer207.33Chemie (NHE)
4H
(B)
DI(HYDROXYETHYL)ETHERnon-polymer106.11Chemie (PEG)
5K, L, M
(A, B, C)
waterwater18.0843Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight99311.8
Non-Polymers*Number of molecules7
Total formula weight1361.8
All*Total formula weight100673.5
*Water molecules are not included.

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PDB entries from 2025-07-16

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