7S5X
Human KATP channel in open conformation, focused on Kir and one SUR, position 1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | ATP-sensitive inward rectifier potassium channel 11 | polymer | 390 | 43622.7 | 4 | UniProt (B2RC52) Pfam (PF01007) Pfam (PF17655) UniProt (by SIFTS) (Q14654) In PDB | Homo sapiens (Human) | Inward rectifier K(+) channel Kir6.2,Potassium channel,inwardly rectifying subfamily J member 11 |
| 2 | E | ATP-binding cassette sub-family C member 8 | polymer | 1582 | 177237.3 | 1 | UniProt (Q09428) Pfam (PF00664) Pfam (PF00005) In PDB | Homo sapiens (Human) | Sulfonylurea receptor 1 |
| 3 | E | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) | |||
| 4 | E | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 5 | E | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 1 | Chemie (ATP) |
Sequence modifications
A, B, C, D: 1 - 390 (UniProt: B2RC52)
E: 3 - 1582 (UniProt: Q09428)
| PDB | External Database | Details |
|---|---|---|
| Ser 166 | Cys 166 | engineered mutation |
| Asp 334 | Gly 334 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | expression tag |
| Gly 2 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 351728.3 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 983.0 | |
| All* | Total formula weight | 352711.2 |
