7S5G
PCSK9 in complex with compound 19
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Propeptide of Proprotein convertase subtilisin/kexin type 9 | polymer | 122 | 13791.5 | 1 | UniProt (Q8NBP7) Pfam (PF05922) In PDB | Homo sapiens (human) | |
2 | B | Proprotein convertase subtilisin/kexin type 9 | polymer | 308 | 32836.9 | 1 | UniProt (Q8NBP7) Pfam (PF00082) In PDB | Homo sapiens (human) | Neural apoptosis-regulated convertase 1,NARC-1,Proprotein convertase 9,PC9,Subtilisin/kexin-like protease PC9 |
3 | C | Z9J-ALA-DAL-PHE-FTR-PRO-THR-0A1-3WX | polymer | 9 | 1265.5 | 1 | synthetic construct | ||
4 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
5 | C | (2E)-but-2-ene-1,4-diol | non-polymer | 88.1 | 1 | Chemie (89N) | |||
6 | water | water | 18.0 | 126 | Chemie (HOH) |
Sequence modifications
B: 153 - 452 (UniProt: Q8NBP7)
PDB | External Database | Details |
---|---|---|
Asn 453 | - | expression tag |
Ser 454 | - | expression tag |
His 455 | - | expression tag |
His 456 | - | expression tag |
His 457 | - | expression tag |
His 458 | - | expression tag |
His 459 | - | expression tag |
His 460 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 47893.9 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 180.2 | |
All* | Total formula weight | 48074.1 |