7S4S

Crystal Structure of SARS-CoV-2 S receptor-binding domain (RBD) in complex CoV11 Fab

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Spike protein S1	polymer	231	26095.3	1	UniProt (P0DTC2) Pfam (PF09408) In PDB	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)
2	H	CoV11 heavy chain	polymer	221	23362.3	1		Homo sapiens
3	L	CoV11 light chain	polymer	216	23536.0	1		Homo sapiens
4	A	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)
5	A, H, L	SULFATE ION	non-polymer		96.1	5	Chemie (SO4)
6	A, H, L	ACETATE ION	non-polymer		59.0	4	Chemie (ACT)
7		water	water		18.0	567	Chemie (HOH)

Sequence modifications

A: 319 - 541 (UniProt: P0DTC2)

PDB	External Database	Details
Ser 542	-	expression tag
Gly 543	-	expression tag
His 544	-	expression tag
His 545	-	expression tag
His 546	-	expression tag
His 547	-	expression tag
His 548	-	expression tag
His 549	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	72993.6
Non-Polymers*	Number of molecules	10
	Total formula weight	937.7
All*	Total formula weight	73931.3

*Water molecules are not included.