7S2R
nanobody bound to IL-2Rg
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Cytokine receptor common subunit gamma | polymer | 209 | 25124.0 | 1 | UniProt (P31785) Pfam (PF22012) Pfam (PF21605) | Homo sapiens (Human) | Interleukin-2 receptor subunit gamma,IL-2 receptor subunit gamma,IL-2R subunit gamma,IL-2RG,gammaC,p64 |
| 2 | B (B) | nanobody gamma-nb6 | polymer | 159 | 17850.5 | 1 | Camelus bactrianus | ||
| 3 | C (C) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 4 | D, E (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 5 | F, G, H, I, N... (A, B) | SULFATE ION | non-polymer | 96.1 | 8 | Chemie (SO4) | |||
| 6 | J, K, L, M, R... (A, B) | GLYCEROL | non-polymer | 92.1 | 6 | Chemie (GOL) | |||
| 7 | T, U (A, B) | water | water | 18.0 | 26 | Chemie (HOH) |
Sequence modifications
A: 55 - 254 (UniProt: P31785)
| PDB | External Database | Details |
|---|---|---|
| Ala 52 | - | cloning artifact |
| Asp 53 | - | cloning artifact |
| Pro 54 | - | cloning artifact |
| His 255 | - | expression tag |
| His 256 | - | expression tag |
| His 257 | - | expression tag |
| His 258 | - | expression tag |
| His 259 | - | expression tag |
| His 260 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 42974.5 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 424.4 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 1763.5 | |
| All* | Total formula weight | 45162.3 |
