7S2N

Crystal structure of the F337L mutation of Trypanosoma cruzi glucokinase in the apo form (open conformation)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Glucokinase 1	polymer	381	42192.6	2	UniProt (Q4E4E1) Pfam (PF02685)	Trypanosoma cruzi (strain CL Brener)
2	C, D (A, B)	water	water		18.0	729	Chemie (HOH)

Sequence modifications

A, B: 1 - 367 (UniProt: Q4E4E1)

PDB	External Database	Details
Met -13	-	initiating methionine
Gly -12	-	expression tag
Arg -11	-	expression tag
Gly -10	-	expression tag
Ser -9	-	expression tag
His -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
Gly -2	-	expression tag
Met -1	-	expression tag
Ala 0	-	expression tag
Leu 337	Phe 337	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	84385.3
All*	Total formula weight	84385.3

*Water molecules are not included.