7S26
ROCK1 IN COMPLEX WITH LIGAND G5018
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | Rho-associated protein kinase 1 | polymer | 398 | 46009.1 | 4 | UniProt (Q13464) Pfam (PF00069) In PDB | Homo sapiens (human) | Renal carcinoma antigen NY-REN-35,Rho-associated,coiled-coil-containing protein kinase 1,coiled-coil-containing protein kinase I,ROCK-I,p160 ROCK-1,p160ROCK |
| 2 | A, B | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 2 | Chemie (EPE) | |||
| 3 | A, B, C | 2-[methyl(phenyl)amino]-1-[4-(1H-pyrrolo[2,3-b]pyridin-3-yl)-3,6-dihydropyridin-1(2H)-yl]ethan-1-one | non-polymer | 346.4 | 3 | Chemie (86K) | |||
| 4 | water | water | 18.0 | 69 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 6 - 402 (UniProt: Q13464)
| PDB | External Database | Details |
|---|---|---|
| Ala 5 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 184036.3 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1515.9 | |
| All* | Total formula weight | 185552.2 |
