7S1Z
Cryo-EM structure of Human NKCC1 K289NA492EL671C
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Solute carrier family 12 member 2 | polymer | 1216 | 131888.6 | 2 | UniProt (P55011) Pfam (PF08403) Pfam (PF00324) Pfam (PF03522) | Homo sapiens (Human) | Basolateral Na-K-Cl symporter,Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2 |
Sequence modifications
A, B: 2 - 1212 (UniProt: P55011)
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Ala -2 | - | expression tag |
| Met -1 | - | expression tag |
| Gly 0 | - | expression tag |
| Ser 1 | - | expression tag |
| Asn 289 | Lys 289 | engineered mutation |
| Glu 492 | Ala 492 | engineered mutation |
| Leu 518 | Ile 518 | conflict |
| Cys 671 | Leu 671 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 263777.3 | |
| All* | Total formula weight | 263777.3 |
