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7S07

Crystal structure of Epstein-Barr virus glycoprotein gH/gL/gp42-peptide in complex with human neutralizing antibodies 769B10 and 769C2

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Envelope glycoprotein Hpolymer65772758.51UniProt (P03231)
Pfam (PF02489)
Pfam (PF17488)
Human gammaherpesvirus 4 (Epstein-Barr virus)gH
2B
(B)
Envelope glycoprotein Lpolymer9810626.11UniProt (P03212)
Pfam (PF11108)
Human gammaherpesvirus 4 (Epstein-Barr virus)gL
3C
(C)
Soluble gp42polymer333766.21UniProt (P0C6Z5)
UniProt (by SIFTS) (P03205)
Human gammaherpesvirus 4 (Epstein-Barr virus)
4D
(X)
769C2 Fab Heavy chainpolymer22523840.71Homo sapiens
5E
(Y)
769C2 Fab Light chainpolymer21522782.01Homo sapiens
6F
(H)
769B10 Fab heavy chainpolymer23425264.31Homo sapiens
7G
(L)
769B10 Fab light chainpolymer21423452.01Homo sapiens
8H, I, J, K
(A, B)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.24Chemie (NAG)
Sequence modifications
B: 27 - 124 (UniProt: P03212)
PDBExternal DatabaseDetails
Ala 35Arg 35conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains7
Total formula weight182489.8
Non-Polymers*Number of molecules4
Total formula weight884.8
All*Total formula weight183374.6
*Water molecules are not included.

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PDB entries from 2025-06-18

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