7RZG
Insulin Degrading Enzyme O/pO
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Cysteine-free Insulin-degrading enzyme | polymer | 1011 | 117068.5 | 2 | UniProt (P14735) Pfam (PF00675) Pfam (PF05193) Pfam (PF16187) In PDB | Homo sapiens (Human) | Abeta-degrading protease,Insulin protease,Insulinase,Insulysin |
Sequence modifications
A, B: 1 - 1011 (UniProt: P14735)
PDB | External Database | Details |
---|---|---|
Leu 110 | Cys 110 | engineered mutation |
Ser 171 | Cys 171 | engineered mutation |
Ala 178 | Cys 178 | engineered mutation |
Val 257 | Cys 257 | engineered mutation |
Leu 414 | Cys 414 | engineered mutation |
Asn 573 | Cys 573 | engineered mutation |
Ser 590 | Cys 590 | engineered mutation |
Ser 789 | Cys 789 | engineered mutation |
Ala 812 | Cys 812 | engineered mutation |
Ala 819 | Cys 819 | engineered mutation |
Ser 904 | Cys 904 | engineered mutation |
Ser 966 | Cys 966 | engineered mutation |
Ser 974 | Cys 974 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 234137.0 | |
All* | Total formula weight | 234137.0 |