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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

7RYZ

Structure of the complex of LBD-TMD part of AMPA receptor GluA2 with auxiliary subunit GSG1L bound to agonist quisqualate

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)		Glutamate receptor 2polymer1154128819.64UniProt (P19491)
Pfam (PF01094)
Pfam (PF10613)
Pfam (PF00060)		Rattus norvegicus (Rat)GluR-2,AMPA-selective glutamate receptor 2,GluR-B,GluR-K2,Glutamate receptor ionotropic,AMPA 2,GluA2
2E, F, G, H
(A, B, C, D)		(S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACIDnon-polymer189.14Chemie (QUS)
Sequence modifications
A, B, C, D: 10 - 998 (UniProt: P19491)
PDBExternal DatabaseDetails
Glu 241Asn 256conflict
Leu 382Val 397conflict
-Leu 399deletion
-Thr 400deletion
-Glu 401deletion
-Leu 402deletion
-Pro 403deletion
-Ser 404deletion
Glu 384Gly 405conflict
Asp 385Asn 406conflict
Gln 392Asn 413conflict
Thr 744Asn 765conflict
Pro 745Ala 766conflict
Ser 754Asn 775conflict
Val 758Leu 779conflict
Ala 775Ser 796conflict
Lys 776Gly 797conflict
Asp 777Gly 798conflict
Ser 778Gly 799conflict
Gly 779Asp 800conflict
Gly 999-expression tag
Thr 1000-expression tag
Gly 1001-expression tag
Lys 1002-expression tag
Thr 1003-expression tag
Ser 1004-expression tag
Arg 1005-expression tag
Arg 1006-expression tag
Gly 1007-expression tag
Arg 1008-expression tag
Ala 1009-expression tag
Leu 1010-expression tag
Leu 1011-expression tag
Ala 1012-expression tag
Val 1013-expression tag
Ala 1014-expression tag
Leu 1015-expression tag
Asn 1016-expression tag
Leu 1017-expression tag
Leu 1018-expression tag
Ala 1019-expression tag
Leu 1020-expression tag
Leu 1021-expression tag
Phe 1022-expression tag
Ala 1023-expression tag
Thr 1024-expression tag
Thr 1025-expression tag
Ala 1026-expression tag
Phe 1027-expression tag
Leu 1028-expression tag
Thr 1029-expression tag
Thr 1030-expression tag
Tyr 1031-expression tag
Trp 1032-expression tag
Cys 1033-expression tag
Gln 1034-expression tag
Gly 1035-expression tag
Thr 1036-expression tag
Gln 1037-expression tag
Arg 1038-expression tag
Val 1039-expression tag
Pro 1040-expression tag
Lys 1041-expression tag
Pro 1042-expression tag
Gly 1043-expression tag
Cys 1044-expression tag
Gly 1045-expression tag
Gln 1046-expression tag
Gly 1047-expression tag
Gly 1048-expression tag
Gly 1049-expression tag
Ala 1050-expression tag
Asn 1051-expression tag
Cys 1052-expression tag
Pro 1053-expression tag
Asn 1054-expression tag
Ser 1055-expression tag
Gly 1056-expression tag
Ala 1057-expression tag
Asn 1058-expression tag
Ala 1059-expression tag
Thr 1060-expression tag
Ala 1061-expression tag
Asn 1062-expression tag
Ser 1063-expression tag
Thr 1064-expression tag
Ala 1065-expression tag
Ala 1066-expression tag
Pro 1067-expression tag
Val 1068-expression tag
Ala 1069-expression tag
Ala 1070-expression tag
Ser 1071-expression tag
Pro 1072-expression tag
Ala 1073-expression tag
Gly 1074-expression tag
Ala 1075-expression tag
Pro 1076-expression tag
Tyr 1077-expression tag
Ser 1078-expression tag
Trp 1079-expression tag
Glu 1080-expression tag
Ala 1081-expression tag
Gly 1082-expression tag
Asp 1083-expression tag
Glu 1084-expression tag
Arg 1085-expression tag
Phe 1086-expression tag
Gln 1087-expression tag
Leu 1088-expression tag
Arg 1089-expression tag
Arg 1090-expression tag
Phe 1091-expression tag
His 1092-expression tag
Thr 1093-expression tag
Gly 1094-expression tag
Ile 1095-expression tag
Trp 1096-expression tag
Tyr 1097-expression tag
Ser 1098-expression tag
Cys 1099-expression tag
Glu 1100-expression tag
Glu 1101-expression tag
Glu 1102-expression tag
Leu 1103-expression tag
Gly 1104-expression tag
Gly 1105-expression tag
Pro 1106-expression tag
Gly 1107-expression tag
Glu 1108-expression tag
Lys 1109-expression tag
Cys 1110-expression tag
Arg 1111-expression tag
Ser 1112-expression tag
Phe 1113-expression tag
Ile 1114-expression tag
Asp 1115-expression tag
Leu 1116-expression tag
Ala 1117-expression tag
Pro 1118-expression tag
Ala 1119-expression tag
Ser 1120-expression tag
Glu 1121-expression tag
Lys 1122-expression tag
Gly 1123-expression tag
Val 1124-expression tag
Leu 1125-expression tag
Trp 1126-expression tag
Leu 1127-expression tag
Ser 1128-expression tag
Val 1129-expression tag
Val 1130-expression tag
Ser 1131-expression tag
Glu 1132-expression tag
Val 1133-expression tag
Leu 1134-expression tag
Tyr 1135-expression tag
Ile 1136-expression tag
Leu 1137-expression tag
Leu 1138-expression tag
Leu 1139-expression tag
Val 1140-expression tag
Val 1141-expression tag
Gly 1142-expression tag
Phe 1143-expression tag
Ser 1144-expression tag
Leu 1145-expression tag
Met 1146-expression tag
Cys 1147-expression tag
Leu 1148-expression tag
Glu 1149-expression tag
Leu 1150-expression tag
Leu 1151-expression tag
His 1152-expression tag
Ser 1153-expression tag
Ser 1154-expression tag
Ser 1155-expression tag
Val 1156-expression tag
Ile 1157-expression tag
Asp 1158-expression tag
Gly 1159-expression tag
Leu 1160-expression tag
Lys 1161-expression tag
Leu 1162-expression tag
Asn 1163-expression tag
Ala 1164-expression tag
Phe 1165-expression tag
Ala 1166-expression tag
Ala 1167-expression tag
Val 1168-expression tag
Phe 1169-expression tag
Thr 1170-expression tag
Val 1171-expression tag
Leu 1172-expression tag
Ser 1173-expression tag
Gly 1174-expression tag
Leu 1175-expression tag
Leu 1176-expression tag
Gly 1177-expression tag
Met 1178-expression tag
Val 1179-expression tag
Ala 1180-expression tag
His 1181-expression tag
Met 1182-expression tag
Met 1183-expression tag
Tyr 1184-expression tag
Thr 1185-expression tag
Gln 1186-expression tag
Val 1187-expression tag
Phe 1188-expression tag
Gln 1189-expression tag
Val 1190-expression tag
Thr 1191-expression tag
Val 1192-expression tag
Ser 1193-expression tag
Leu 1194-expression tag
Gly 1195-expression tag
Pro 1196-expression tag
Glu 1197-expression tag
Asp 1198-expression tag
Trp 1199-expression tag
Arg 1200-expression tag
Pro 1201-expression tag
His 1202-expression tag
Ser 1203-expression tag
Trp 1204-expression tag
Asp 1205-expression tag
Tyr 1206-expression tag
Gly 1207-expression tag
Trp 1208-expression tag
Ser 1209-expression tag
Phe 1210-expression tag
Cys 1211-expression tag
Leu 1212-expression tag
Ala 1213-expression tag
Trp 1214-expression tag
Gly 1215-expression tag
Ser 1216-expression tag
Phe 1217-expression tag
Thr 1218-expression tag
Cys 1219-expression tag
Cys 1220-expression tag
Met 1221-expression tag
Ala 1222-expression tag
Ala 1223-expression tag
Ser 1224-expression tag
Val 1225-expression tag
Thr 1226-expression tag
Thr 1227-expression tag
Leu 1228-expression tag
Asn 1229-expression tag
Ser 1230-expression tag
Tyr 1231-expression tag
Thr 1232-expression tag
Lys 1233-expression tag
Thr 1234-expression tag
Val 1235-expression tag
Ile 1236-expression tag
Glu 1237-expression tag
Phe 1238-expression tag
Arg 1239-expression tag
His 1240-expression tag
Lys 1241-expression tag
Arg 1242-expression tag
Lys 1243-expression tag
Val 1244-expression tag
Phe 1245-expression tag
Glu 1246-expression tag
Gln 1247-expression tag
Gly 1248-expression tag
Tyr 1249-expression tag
Arg 1250-expression tag
Glu 1251-expression tag
Glu 1252-expression tag
Pro 1253-expression tag
Thr 1254-expression tag
Phe 1255-expression tag
Ile 1256-expression tag
Asp 1257-expression tag
Pro 1258-expression tag
Glu 1259-expression tag
Ala 1260-expression tag
Ile 1261-expression tag
Lys 1262-expression tag
Tyr 1263-expression tag
Phe 1264-expression tag
Arg 1265-expression tag
Glu 1266-expression tag
Arg 1267-expression tag
Ile 1268-expression tag
Glu 1269-expression tag
Lys 1270-expression tag
Gly 1271-expression tag
Asp 1272-expression tag
Val 1273-expression tag
Ser 1274-expression tag
Glu 1275-expression tag
Glu 1276-expression tag
Glu 1277-expression tag
Asp 1278-expression tag
Phe 1279-expression tag
Arg 1280-expression tag
Leu 1281-expression tag
Ala 1282-expression tag
Cys 1283-expression tag
Arg 1284-expression tag
His 1285-expression tag
Glu 1286-expression tag
Arg 1287-expression tag
Tyr 1288-expression tag
Pro 1289-expression tag
Thr 1290-expression tag
Arg 1291-expression tag
His 1292-expression tag
Gln 1293-expression tag
Pro 1294-expression tag
His 1295-expression tag
Met 1296-expression tag
Gly 1297-expression tag
Asp 1298-expression tag
Ser 1299-expression tag
Trp 1300-expression tag
Pro 1301-expression tag
Arg 1302-expression tag
Ser 1303-expression tag
Ser 1304-expression tag
Ala 1305-expression tag
His 1306-expression tag
Glu 1307-expression tag
Ala 1308-expression tag
Ala 1309-expression tag
Glu 1310-expression tag
Leu 1311-expression tag
Asn 1312-expression tag
Arg 1313-expression tag
Gln 1314-expression tag
Cys 1315-expression tag
Trp 1316-expression tag
Val 1317-expression tag
Leu 1318-expression tag
Gly 1319-expression tag
His 1320-expression tag
Trp 1321-expression tag
Val 1322-expression tag
Gly 1323-expression tag
Thr 1324-expression tag
Gly 1325-expression tag
Gly 1326-expression tag
Leu 1327-expression tag
Val 1328-expression tag
Pro 1329-expression tag
Arg 1330-expression tag
Gly 1331-expression tag
Ser 1332-expression tag
Ala 1333-expression tag
Ala 1334-expression tag
Ala 1335-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight515278.4
Non-Polymers*Number of molecules4
Total formula weight756.5
All*Total formula weight516034.9
*Water molecules are not included.

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PDB entries from 2024-11-06

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