7RYO
CD1a-dideoxymycobactin-gdTCR complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | T-cell surface glycoprotein CD1a | polymer | 286 | 32593.6 | 1 | UniProt (P06126) Pfam (PF16497) Pfam (PF07654) | Homo sapiens (Human) | T-cell surface antigen T6/Leu-6,hTa1 thymocyte antigen |
| 2 | B (B) | Beta-2-microglobulin | polymer | 108 | 12602.1 | 1 | UniProt (P61769) Pfam (PF07654) | Homo sapiens (Human) | |
| 3 | C (C) | T cell receptor gamma variable 4,T cell receptor beta constant 1 | polymer | 248 | 27987.1 | 1 | UniProt (A0A0C4DH28) UniProt (P01850) Pfam (PF07686) Pfam (PF07654) | Homo sapiens (Human) | |
| 4 | D (D) | T cell receptor delta variable 1,T cell receptor alpha chain constant | polymer | 209 | 23622.6 | 1 | UniProt (A0A1B0GX56) UniProt (P01848) Pfam (PF07686) Pfam (PF09291) | Homo sapiens (Human) | |
| 5 | E, F (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 6 | G (A) | dideoxymycobactin-838 | non-polymer | 838.1 | 1 | Chemie (WGR) | |||
| 7 | H (D) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) |
Sequence modifications
A: 1 - 278 (UniProt: P06126)
B: 2 - 100 (UniProt: P61769)
C: 3 - 102 (UniProt: A0A0C4DH28)
C: 120 - 248 (UniProt: P01850)
D: 2 - 96 (UniProt: A0A1B0GX56)
D: 117 - 209 (UniProt: P01848)
| PDB | External Database | Details |
|---|---|---|
| Asp -1 | - | expression tag |
| Ala 0 | - | expression tag |
| Thr 2 | Asp 19 | conflict |
| Ile 13 | Thr 30 | variant |
| Trp 51 | Cys 68 | variant |
| Gly 279 | - | expression tag |
| Ser 280 | - | expression tag |
| Leu 281 | - | expression tag |
| Val 282 | - | expression tag |
| Pro 283 | - | expression tag |
| Arg 284 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Asp -1 | - | expression tag |
| Ala 0 | - | expression tag |
| Gly 1 | - | expression tag |
| Gly 101 | - | expression tag |
| Ser 102 | - | expression tag |
| Leu 103 | - | expression tag |
| Val 104 | - | expression tag |
| Pro 105 | - | expression tag |
| Arg 106 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | initiating methionine |
| Ala 2 | - | expression tag |
| Asp 103 | - | linker |
| Tyr 104 | - | linker |
| Tyr 105 | - | linker |
| Lys 106 | - | linker |
| Lys 107 | - | linker |
| Leu 108 | - | linker |
| Phe 109 | - | linker |
| Gly 110 | - | linker |
| Ser 111 | - | linker |
| Gly 112 | - | linker |
| Thr 113 | - | linker |
| Thr 114 | - | linker |
| Leu 115 | - | linker |
| Val 116 | - | linker |
| Val 117 | - | linker |
| Thr 118 | - | linker |
| Glu 119 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Lys 122 | Asn 3 | conflict |
| Asn 123 | Lys 4 | conflict |
| Tyr 155 | Phe 36 | conflict |
| Cys 175 | Ser 56 | engineered mutation |
| Ala 193 | Cys 74 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | initiating methionine |
| Leu 97 | - | linker |
| Arg 98 | - | linker |
| Trp 99 | - | linker |
| Pro 100 | - | linker |
| Asp 101 | - | linker |
| Lys 102 | - | linker |
| Leu 103 | - | linker |
| Ile 104 | - | linker |
| Phe 105 | - | linker |
| Gly 106 | - | linker |
| Lys 107 | - | linker |
| Gly 108 | - | linker |
| Thr 109 | - | linker |
| Arg 110 | - | linker |
| Val 111 | - | linker |
| Thr 112 | - | linker |
| Val 113 | - | linker |
| Glu 114 | - | linker |
| Pro 115 | - | linker |
| Asn 116 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Cys 163 | Thr 47 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 96805.3 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1058.3 | |
| All* | Total formula weight | 97863.7 |
