7RXX
Human Methionine Adenosyltransferase 2A bound to Methylthioadenosine and two sulfate in the active site
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | S-adenosylmethionine synthase isoform type-2 | polymer | 417 | 46279.4 | 1 | UniProt (P31153) Pfam (PF00438) Pfam (PF02772) Pfam (PF02773) In PDB | Homo sapiens (Human) | AdoMet synthase 2,Methionine adenosyltransferase 2,MAT 2,Methionine adenosyltransferase II,MAT-II |
2 | A | ALANINE | non-polymer | 89.1 | 1 | Chemie (ALA) | |||
3 | A | 5'-DEOXY-5'-METHYLTHIOADENOSINE | non-polymer | 297.3 | 1 | Chemie (MTA) | |||
4 | A | 3,6,9,12,15-PENTAOXAHEPTADECANE | non-polymer | 250.3 | 1 | Chemie (P3G) | |||
5 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
6 | A | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
7 | A | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
8 | A | POTASSIUM ION | non-polymer | 39.1 | 1 | Chemie (K) | |||
9 | A | SODIUM ION | non-polymer | 23.0 | 4 | Chemie (NA) | |||
10 | water | water | 18.0 | 368 | Chemie (HOH) |
Sequence modifications
A: 1 - 395 (UniProt: P31153)
PDB | External Database | Details |
---|---|---|
Met -21 | - | expression tag |
His -20 | - | expression tag |
His -19 | - | expression tag |
His -18 | - | expression tag |
His -17 | - | expression tag |
His -16 | - | expression tag |
His -15 | - | expression tag |
Ser -14 | - | expression tag |
Ser -13 | - | expression tag |
Gly -12 | - | expression tag |
Val -11 | - | expression tag |
Asp -10 | - | expression tag |
Leu -9 | - | expression tag |
Gly -8 | - | expression tag |
Thr -7 | - | expression tag |
Glu -6 | - | expression tag |
Asn -5 | - | expression tag |
Leu -4 | - | expression tag |
Tyr -3 | - | expression tag |
Phe -2 | - | expression tag |
Gln -1 | - | expression tag |
Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 46279.4 | |
Non-Polymers* | Number of molecules | 13 |
Total formula weight | 1070.6 | |
All* | Total formula weight | 47350.0 |