7RWP
Crystal Structure of BPTF bromodomain in complex with 5-[4-(aminomethyl)anilino]-4-chloro-2-methylpyridazin-3(2H)-one
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Nucleosome-remodeling factor subunit BPTF | polymer | 131 | 15408.4 | 1 | UniProt (Q12830) Pfam (PF00439) In PDB | Homo sapiens (Human) | Bromodomain and PHD finger-containing transcription factor,Fetal Alz-50 clone 1 protein,Fetal Alzheimer antigen |
2 | A | 5-[4-(aminomethyl)anilino]-4-chloro-2-methylpyridazin-3(2H)-one | non-polymer | 264.7 | 1 | Chemie (7WZ) | |||
3 | A | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
4 | water | water | 18.0 | 199 | Chemie (HOH) |
Sequence modifications
A: 2917 - 3037 (UniProt: Q12830)
PDB | External Database | Details |
---|---|---|
Gly 2907 | - | expression tag |
Thr 2908 | - | expression tag |
Glu 2909 | - | expression tag |
Asn 2910 | - | expression tag |
Leu 2911 | - | expression tag |
Tyr 2912 | - | expression tag |
Phe 2913 | - | expression tag |
Gln 2914 | - | expression tag |
Ser 2915 | - | expression tag |
Met 2916 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 15408.4 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 304.8 | |
All* | Total formula weight | 15713.2 |