7RUV
Structure of Human ATP:Cobalamin Adenosyltransferase E193K bound to adenosylcobalamin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | Corrinoid adenosyltransferase | polymer | 196 | 21720.8 | 4 | UniProt (Q96EY8) Pfam (PF01923) In PDB | Homo sapiens (Human) | Cob(II)alamin adenosyltransferase,Cob(II)yrinic acid a,c-diamide adenosyltransferase,Cobinamide/cobalamin adenosyltransferase,Methylmalonic aciduria type B protein |
| 2 | A | POTASSIUM ION | non-polymer | 39.1 | 1 | Chemie (K) | |||
| 3 | A, C | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 4 | A, B, C, D | COBALAMIN | non-polymer | 1330.4 | 4 | Chemie (B12) | |||
| 5 | A, B, C, D | 5'-DEOXYADENOSINE | non-polymer | 251.2 | 4 | Chemie (5AD) | |||
| 6 | C | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 7 | water | water | 18.0 | 113 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 56 - 250 (UniProt: Q96EY8)
| PDB | External Database | Details |
|---|---|---|
| Met 55 | - | initiating methionine |
| Lys 193 | Glu 193 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 86883.0 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 6506.2 | |
| All* | Total formula weight | 93389.2 |
