7RUV
Structure of Human ATP:Cobalamin Adenosyltransferase E193K bound to adenosylcobalamin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Corrinoid adenosyltransferase | polymer | 196 | 21720.8 | 4 | UniProt (Q96EY8) Pfam (PF01923) | Homo sapiens (Human) | Cob(II)alamin adenosyltransferase,Cob(II)yrinic acid a,c-diamide adenosyltransferase,Cobinamide/cobalamin adenosyltransferase,Methylmalonic aciduria type B protein |
| 2 | E (A) | POTASSIUM ION | non-polymer | 39.1 | 1 | Chemie (K) PubChem (813) | |||
| 3 | F, L (A, C) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) PubChem (888) | |||
| 4 | G, I, M, O (A, B, C, D) | COBALAMIN | non-polymer | 1330.4 | 4 | Chemie (B12) | |||
| 5 | H, J, N, P (A, B, C, D) | 5'-DEOXYADENOSINE | non-polymer | 251.2 | 4 | Chemie (5AD) PubChem (16725083) PubChem (142) PubChem (23638944) PubChem (25201172) PubChem (25796474) PubChem (25796475) PubChem (40467848) PubChem (71678) PubChem (23615209) PubChem (40467849) PubChem (57115448) PubChem (439182) PubChem (59731278) PubChem (449044) PubChem (1277776) PubChem (90321697) PubChem (676784) PubChem (6541038) PubChem (6398669) PubChem (6928544) PubChem (121275112) PubChem (124363198) PubChem (12827542) PubChem (133636852) PubChem (140689696) PubChem (142801875) PubChem (142801934) | |||
| 6 | K (C) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) PubChem (753) | |||
| 7 | Q, R, S, T (A, B, C, D) | water | water | 18.0 | 113 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 56 - 250 (UniProt: Q96EY8)
| PDB | External Database | Details |
|---|---|---|
| Met 55 | - | initiating methionine |
| Lys 193 | Glu 193 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 86883.0 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 6506.2 | |
| All* | Total formula weight | 93389.2 |
