7RUU
Structure of Human ATP:Cobalamin Adenosyltransferase R190C bound to adenosylcobalamin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Corrinoid adenosyltransferase | polymer | 196 | 21666.6 | 4 | UniProt (Q96EY8) Pfam (PF01923) | Homo sapiens (Human) | Cob(II)alamin adenosyltransferase,Cob(II)yrinic acid a,c-diamide adenosyltransferase,Cobinamide/cobalamin adenosyltransferase,Methylmalonic aciduria type B protein |
| 2 | E, J, M, Q, T (A, B, C, D) | ACETATE ION | non-polymer | 59.0 | 5 | Chemie (ACT) | |||
| 3 | F, G, N (A, C) | POTASSIUM ION | non-polymer | 39.1 | 3 | Chemie (K) | |||
| 4 | H, K, O, R (A, B, C, D) | 5'-DEOXYADENOSINE | non-polymer | 251.2 | 4 | Chemie (5AD) | |||
| 5 | I, L, P, S (A, B, C, D) | COBALAMIN | non-polymer | 1330.4 | 4 | Chemie (B12) | |||
| 6 | U, V, W, X (A, B, C, D) | water | water | 18.0 | 248 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 56 - 250 (UniProt: Q96EY8)
| PDB | External Database | Details |
|---|---|---|
| Met 55 | - | initiating methionine |
| Cys 190 | Arg 190 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 86666.6 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 6738.9 | |
| All* | Total formula weight | 93405.5 |
