7RUI
Bromodomain-containing protein 4 (BRD4) bromodomain 1 (BD1) complexed with XR844
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Bromodomain-containing protein 4 | polymer | 127 | 15123.4 | 1 | UniProt (O60885) Pfam (PF00439) In PDB | Homo sapiens (Human) | Protein HUNK1 |
| 2 | A | N-{1-[1,1-di(pyridin-2-yl)ethyl]-6-(5-{[(2-fluorophenyl)carbamoyl]amino}-1-methyl-6-oxo-1,6-dihydropyridin-3-yl)-1H-indol-4-yl}-2,2,2-trifluoroethane-1-sulfonamide | non-polymer | 719.7 | 1 | Chemie (7QZ) | |||
| 3 | water | water | 18.0 | 119 | Chemie (HOH) |
Sequence modifications
A: 44 - 168 (UniProt: O60885)
| PDB | External Database | Details |
|---|---|---|
| Leu 42 | - | expression tag |
| Glu 43 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 15123.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 719.7 | |
| All* | Total formula weight | 15843.1 |
