7RPO
Archaeal DNA ligase and heterotrimeric PCNA in complex with non-ligatable DNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DNA polymerase sliding clamp 1 | polymer | 258 | 28712.0 | 1 | UniProt (P57766) Pfam (PF00705) | Saccharolobus solfataricus (Sulfolobus solfataricus) | Proliferating cell nuclear antigen homolog 1,PCNA1 |
| 2 | B (B) | DNA polymerase sliding clamp 2 | polymer | 245 | 27461.1 | 1 | UniProt (Q97Z84) Pfam (PF00705) Pfam (PF02747) | Saccharolobus solfataricus (Sulfolobus solfataricus) | Proliferating cell nuclear antigen homolog 2,PCNA2 |
| 3 | C (C) | DNA polymerase sliding clamp 3 | polymer | 252 | 28560.3 | 1 | UniProt (P57765) Pfam (PF00705) Pfam (PF02747) | Saccharolobus solfataricus (Sulfolobus solfataricus) | Proliferating cell nuclear antigen homolog 3,PCNA3 |
| 4 | D (X) | Upstream strand DNA | polymer | 24 | 7376.8 | 1 | Homo sapiens | ||
| 5 | E (Y) | Downstream strand DNA | polymer | 23 | 7127.6 | 1 | Homo sapiens | ||
| 6 | F (Z) | Template strand DNA | polymer | 47 | 14403.3 | 1 | Homo sapiens | ||
| 7 | G (E) | DNA ligase | polymer | 621 | 69998.4 | 1 | UniProt (Q980T8) Pfam (PF04675) Pfam (PF01068) Pfam (PF04679) | Saccharolobus solfataricus (Sulfolobus solfataricus) | Polydeoxyribonucleotide synthase [ATP] |
| 8 | H, I, K, L (X, E) | MANGANESE (II) ION | non-polymer | 54.9 | 4 | Chemie (MN) | |||
| 9 | J (E) | ADENOSINE MONOPHOSPHATE | non-polymer | 347.2 | 1 | Chemie (AMP) |
Sequence modifications
A: 2 - 249 (UniProt: P57766)
C: 1 - 244 (UniProt: P57765)
E: 1 - 601 (UniProt: Q980T8)
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
| Ala 1 | - | expression tag |
| Leu 250 | - | expression tag |
| Glu 251 | - | expression tag |
| His 252 | - | expression tag |
| His 253 | - | expression tag |
| His 254 | - | expression tag |
| His 255 | - | expression tag |
| His 256 | - | expression tag |
| His 257 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Leu 245 | - | expression tag |
| Glu 246 | - | expression tag |
| His 247 | - | expression tag |
| His 248 | - | expression tag |
| His 249 | - | expression tag |
| His 250 | - | expression tag |
| His 251 | - | expression tag |
| His 252 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Met -19 | - | initiating methionine |
| Gly -18 | - | expression tag |
| Ser -17 | - | expression tag |
| Ser -16 | - | expression tag |
| His -15 | - | expression tag |
| His -14 | - | expression tag |
| His -13 | - | expression tag |
| His -12 | - | expression tag |
| His -11 | - | expression tag |
| His -10 | - | expression tag |
| Ser -9 | - | expression tag |
| Ser -8 | - | expression tag |
| Gly -7 | - | expression tag |
| Leu -6 | - | expression tag |
| Val -5 | - | expression tag |
| Pro -4 | - | expression tag |
| Arg -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 7 |
| Total formula weight | 183639.3 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 567.0 | |
| All* | Total formula weight | 184206.3 |
