7RPF
X-ray crystal structure of OXA-24/40 in complex with doripenem
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Beta-lactamase | polymer | 245 | 27717.9 | 1 | UniProt (Q8RLA6) Pfam (PF00905) | Acinetobacter baumannii | Carbapenem-hydrolyzing beta-lactamase OXA-40,Carbapenem-hydrolyzing class D beta-lactamase OXA-24,Carbapenem-hydrolyzing oxacillinase,Carbapenem-hydrolyzing oxacillinase OXA-40,Carbapenemase OXA-24,Class D beta-lactamase OXA-40,OXA-24 class D beta-lactamase,OXA24 B-lactamase,Oxa40 |
| 2 | B (A) | BICARBONATE ION | non-polymer | 61.0 | 1 | Chemie (BCT) | |||
| 3 | C (A) | (4R,5S)-5-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-4-methyl-3-({(3S,5S)-5-[(sulfamoylamino)methyl]pyrrolidin-3-yl}sulfanyl)-4,5-dihydro-1H-pyrrole-2-carboxylic acid | non-polymer | 422.5 | 1 | Chemie (4J6) | |||
| 4 | D (A) | (2S,3R,4S)-2-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-3-methyl-4-({(3S,5S)-5-[(sulfamoylamino)methyl]pyrrolidin-3-yl}sulfanyl)-3,4-dihydro-2H-pyrrole-5-carboxylic acid | non-polymer | 422.5 | 1 | Chemie (DRW) | |||
| 5 | E, F, G (A) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 6 | H (A) | water | water | 18.0 | 190 | Chemie (HOH) |
Sequence modifications
A: 32 - 275 (UniProt: Q8RLA6)
| PDB | External Database | Details |
|---|---|---|
| Met 31 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 27717.9 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1194.2 | |
| All* | Total formula weight | 28912.1 |
