7RPD
X-ray crystal structure of OXA-24/40 V130D in complex with ertapenem
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Beta-lactamase | polymer | 245 | 27690.8 | 1 | UniProt (Q8RLA6) Pfam (PF00905) In PDB | Acinetobacter baumannii | Carbapenem-hydrolyzing beta-lactamase OXA-40,Carbapenem-hydrolyzing class D beta-lactamase OXA-24,Carbapenem-hydrolyzing oxacillinase,Carbapenem-hydrolyzing oxacillinase OXA-40,Carbapenemase OXA-24,Class D beta-lactamase OXA-40,OXA-24 class D beta-lactamase,OXA24 B-lactamase,Oxa40 |
| 2 | A | (4R,5S)-3-({(3S,5S)-5-[(3-carboxyphenyl)carbamoyl]pyrrolidin-3-yl}sulfanyl)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-4-methyl-4,5-dihydro-1H-pyrrole-2-carboxylic acid | non-polymer | 477.5 | 1 | Chemie (1RG) | |||
| 3 | A | BICARBONATE ION | non-polymer | 61.0 | 2 | Chemie (BCT) | |||
| 4 | A | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 5 | water | water | 18.0 | 100 | Chemie (HOH) |
Sequence modifications
A: 32 - 275 (UniProt: Q8RLA6)
| PDB | External Database | Details |
|---|---|---|
| Met 31 | - | expression tag |
| Asp 130 | Val 130 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 27690.8 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 695.6 | |
| All* | Total formula weight | 28386.4 |
