7RPC
X-ray crystal structure of OXA-24/40 K84D in complex with ertapenem
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Beta-lactamase | polymer | 245 | 27660.8 | 1 | UniProt (Q8RLA6) Pfam (PF00905) In PDB | Acinetobacter baumannii | Carbapenem-hydrolyzing beta-lactamase OXA-40,Carbapenem-hydrolyzing class D beta-lactamase OXA-24,Carbapenem-hydrolyzing oxacillinase,Carbapenem-hydrolyzing oxacillinase OXA-40,Carbapenemase OXA-24,Class D beta-lactamase OXA-40,OXA-24 class D beta-lactamase,OXA24 B-lactamase,Oxa40 |
| 2 | A | BICARBONATE ION | non-polymer | 61.0 | 1 | Chemie (BCT) | |||
| 3 | A | (1S,4R,5S,6S)-3-{[(3S,5S)-5-carbamoylpyrrolidin-3-yl]sulfanyl}-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid | non-polymer | 355.4 | 1 | Chemie (6H7) | |||
| 4 | A | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 5 | water | water | 18.0 | 35 | Chemie (HOH) |
Sequence modifications
A: 32 - 275 (UniProt: Q8RLA6)
| PDB | External Database | Details |
|---|---|---|
| Met 31 | - | initiating methionine |
| Asp 84 | Lys 84 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 27660.8 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 512.5 | |
| All* | Total formula weight | 28173.2 |
