7ROU
Structure of human tyrosyl tRNA synthetase in complex with ML901-Tyr
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Tyrosine--tRNA ligase, cytoplasmic | polymer | 365 | 41119.5 | 1 | UniProt (P54577) Pfam (PF00579) In PDB | Homo sapiens (Human) | Tyrosyl-tRNA synthetase,TyrRS |
| 2 | A | {(2R,3S,4R,5R)-5-[4-amino-3-(difluoromethoxy)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-3,4-dihydroxyoxolan-2-yl}methyl [(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]sulfamate (non-preferred name) | non-polymer | 575.5 | 1 | Chemie (66I) | |||
| 3 | A | SULFATE ION | non-polymer | 96.1 | 7 | Chemie (SO4) | |||
| 4 | water | water | 18.0 | 296 | Chemie (HOH) |
Sequence modifications
A: 1 - 364 (UniProt: P54577)
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 41119.5 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1247.9 | |
| All* | Total formula weight | 42367.4 |
