7RNU
nSH2 domain of p85-beta subunit of phosphatidylinositol 3-kinase in complex with an actin peptide with phosphorylated tyrosine 53
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, G (A, C, E, G) | Phosphatidylinositol 3-kinase regulatory subunit beta | polymer | 114 | 13029.5 | 4 | UniProt (O00459) Pfam (PF00017) | Homo sapiens (Human) | PI3-kinase regulatory subunit beta,PI3K regulatory subunit beta,PtdIns-3-kinase regulatory subunit beta,Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta,PI3-kinase subunit p85-beta,PtdIns-3-kinase regulatory subunit p85-beta |
| 2 | B, D, F, H (B, D, F, H) | Actin, alpha skeletal muscle | polymer | 9 | 1064.0 | 4 | UniProt (P68133) | Homo sapiens | Alpha-actin-1 |
| 3 | I, J, K, L, M... (A, C, G) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 8 | Chemie (EDO) | |||
| 4 | Q, R, S, T, U... (A, B, C, D, E...) | water | water | 18.0 | 404 | Chemie (HOH) |
Sequence modifications
A, C, E, G: 321 - 431 (UniProt: O00459)
| PDB | External Database | Details |
|---|---|---|
| Gly 318 | - | expression tag |
| Ser 319 | - | expression tag |
| Met 320 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 56373.9 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 496.5 | |
| All* | Total formula weight | 56870.5 |
