7RNS
nSH2 domain of p85-alpha subunit of phosphatidylinositol 3-kinase in complex with an actin peptide with phosphorylated tyrosine 53
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Isoform 2 of Phosphatidylinositol 3-kinase regulatory subunit alpha | polymer | 117 | 13516.1 | 1 | UniProt (P27986) Pfam (PF00017) In PDB | Homo sapiens (Human) | PI3-kinase regulatory subunit alpha,PI3K regulatory subunit alpha,PtdIns-3-kinase regulatory subunit alpha,Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha,PI3-kinase subunit p85-alpha,PtdIns-3-kinase regulatory subunit p85-alpha |
| 2 | B | Actin, alpha skeletal muscle | polymer | 9 | 1064.0 | 1 | UniProt (P68133) In PDB | Homo sapiens | Alpha-actin-1 |
| 3 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 6 | Chemie (EDO) | |||
| 4 | water | water | 18.0 | 196 | Chemie (HOH) |
Sequence modifications
A: 321 - 434 (UniProt: P27986)
| PDB | External Database | Details |
|---|---|---|
| Gly 318 | - | expression tag |
| Ser 319 | - | expression tag |
| Met 320 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 14580.1 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 372.4 | |
| All* | Total formula weight | 14952.5 |
