7RMP
Structure of ACLY D1026A - substrates-asym
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | ATP-citrate synthase | polymer | 1101 | 120940.1 | 4 | UniProt (P53396) Pfam (PF24948) Pfam (PF16114) Pfam (PF02629) Pfam (PF00549) Pfam (PF00285) | Homo sapiens (human) | ATP-citrate (pro-S-)-lyase,ACL,Citrate cleavage enzyme |
| 2 | E, K, T (A, B, D) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 3 | Chemie (ADP) | |||
| 3 | F, L, U (A, B, D) | (3S)-citryl-Coenzyme A | non-polymer | 941.6 | 3 | Chemie (Q5B) | |||
| 4 | G, M, Q, V (A, B, C, D) | CITRATE ANION | non-polymer | 189.1 | 4 | Chemie (FLC) | |||
| 5 | H, R (A, C) | UNKNOWN LIGAND | non-polymer | 767.5 | 2 | Chemie (UNL) | |||
| 6 | I, N, P, S (A, B, C, D) | COENZYME A | non-polymer | 767.5 | 4 | Chemie (COA) | |||
| 7 | J, O, W (A, B, D) | PHOSPHATE ION | non-polymer | 95.0 | 3 | Chemie (PO4) | |||
| 8 | AA, X, Y, Z (D, A, B, C) | water | water | 18.0 | 41 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 1101 (UniProt: P53396)
| PDB | External Database | Details |
|---|---|---|
| Ala 1026 | Asp 1026 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 483760.5 | |
| Non-Polymers* | Number of molecules | 19 |
| Total formula weight | 9753.0 | |
| All* | Total formula weight | 493513.5 |
