7RLC

Cryo-EM structure of human p97-A232E mutant bound to ATPgS.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	Transitional endoplasmic reticulum ATPase	polymer	821	91289.7	6	UniProt (P55072) Pfam (PF02359) Pfam (PF02933) Pfam (PF00004) Pfam (PF17862) In PDB	Homo sapiens (Human)	TER ATPase,15S Mg(2+)-ATPase p97 subunit,Valosin-containing protein,VCP
2	F, A, B, C, D...	PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER	non-polymer		523.2	12	Chemie (AGS)
3	F, A, B, C, D...	MAGNESIUM ION	non-polymer		24.3	12	Chemie (MG)

Sequence modifications

A, B, C, D, E, F: 2 - 806 (UniProt: P55072)

PDB	External Database	Details
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
Gly -8	-	expression tag
Thr -7	-	expression tag
Ser -6	-	expression tag
Glu -5	-	expression tag
Asn -4	-	expression tag
Leu -3	-	expression tag
Tyr -2	-	expression tag
Phe -1	-	expression tag
Gln 0	-	expression tag
Gly 1	-	expression tag
Glu 232	Ala 232	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	547738.1
Non-Polymers*	Number of molecules	24
	Total formula weight	6570.6
All*	Total formula weight	554308.7

*Water molecules are not included.