7RJQ
Crystal structure of human Bromodomain containing protein 4 (BRD4) in complex with ILF3
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Bromodomain-containing protein 4 | polymer | 127 | 15099.4 | 1 | UniProt (O60885) Pfam (PF00439) | Homo sapiens (Human) | Protein HUNK1 |
| 2 | B (B) | Interleukin enhancer-binding factor 3 | polymer | 8 | 883.1 | 1 | UniProt (Q12906) | Homo sapiens | Double-stranded RNA-binding protein 76,DRBP76,M-phase phosphoprotein 4,MPP4,Nuclear factor associated with dsRNA,NFAR,Nuclear factor of activated T-cells 90 kDa,NF-AT-90,Translational control protein 80,TCP80 |
| 3 | C, D, E, F, G (A) | SODIUM ION | non-polymer | 23.0 | 5 | Chemie (NA) | |||
| 4 | H, I, K (A, B) | CHLORIDE ION | non-polymer | 35.5 | 3 | Chemie (CL) | |||
| 5 | J (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 6 | L, M (A, B) | water | water | 18.0 | 82 | Chemie (HOH) |
Sequence modifications
A: 44 - 168 (UniProt: O60885)
| PDB | External Database | Details |
|---|---|---|
| Ser 42 | - | expression tag |
| Met 43 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 15982.5 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 283.4 | |
| All* | Total formula weight | 16265.8 |
