7RJL
Crystal structure of human Bromodomain containing protein 3 (BRD3) in complex with SHMT
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Bromodomain-containing protein 3 | polymer | 123 | 14586.8 | 2 | UniProt (Q15059) Pfam (PF00439) | Homo sapiens (Human) | RING3-like protein |
| 2 | C, D (C, D) | Serine hydroxymethyltransferase, cytosolic | polymer | 6 | 758.9 | 2 | UniProt (P34896) | Homo sapiens | SHMT,Glycine hydroxymethyltransferase,Serine methylase |
| 3 | E, F, G, H, I... (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 8 | Chemie (EDO) | |||
| 4 | K (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | N, O, P, Q (A, B, C, D) | water | water | 18.0 | 193 | Chemie (HOH) |
Sequence modifications
A, B: 24 - 144 (UniProt: Q15059)
| PDB | External Database | Details |
|---|---|---|
| Ser 22 | - | expression tag |
| Met 23 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 30691.5 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 588.6 | |
| All* | Total formula weight | 31280.1 |
