7RIU
human PXR LBD bound to GSK002
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Isoform 1C of Nuclear receptor subfamily 1 group I member 2 | polymer | 298 | 34187.6 | 1 | UniProt (O75469) Pfam (PF00104) | Homo sapiens (Human) | Orphan nuclear receptor PAR1,Orphan nuclear receptor PXR,Pregnane X receptor,Steroid and xenobiotic receptor,SXR |
| 2 | B (A) | N-{3-[5-(2-aminopyrimidin-4-yl)-2-tert-butyl-1,3-thiazol-4-yl]-2-fluorophenyl}thiophene-3-sulfonamide | non-polymer | 489.6 | 1 | Chemie (5YU) | |||
| 3 | C (A) | water | water | 18.0 | 146 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34187.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 489.6 | |
| All* | Total formula weight | 34677.2 |
