7RIO
human PXR LBD bound to GSK003
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Isoform 1C of Nuclear receptor subfamily 1 group I member 2 | polymer | 298 | 34187.6 | 1 | UniProt (O75469) Pfam (PF00104) In PDB | Homo sapiens (Human) | Orphan nuclear receptor PAR1,Orphan nuclear receptor PXR,Pregnane X receptor,Steroid and xenobiotic receptor,SXR |
2 | A | N-[3-(2-tert-butyl-5-{2-[2-(methanesulfonyl)ethyl]pyrimidin-4-yl}-1,3-thiazol-4-yl)-2-fluorophenyl]-2,5-difluorobenzene-1-sulfonamide | non-polymer | 610.7 | 1 | Chemie (5YX) | |||
3 | water | water | 18.0 | 84 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 34187.6 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 610.7 | |
All* | Total formula weight | 34798.3 |